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Human Rad51 filaments on double- and single-stranded DNA: correlating frequent and irregular kinds with recombination functionality.
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first at any time research of your dynamics DNA supercoils and the discovery of supercoil hopping
Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
Considering the fact that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his investigation has focused on researching cell division with germs on chip, though his ultimate fascination is inside the direction of noticing synthetic cells.
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue
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Resolving the step dimension in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating procedure
An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes
Lots of new phenomena ended up found, and he and his research team established a number one place Within this industry of analysis. Dekker and his research team found new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the main to create a transistor according to one nanotube molecule.
2005, discovery of the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of long-selection conformational changes in Mre11/DNA mend complexes; and first pressure measurements with a DNA molecule within a nanopore
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen cees dekker in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)